How to participate

To assure technical and oncological quality of the TaTME technique, all participating centers will be conducted a surgical quality assessment . The end product of a Delphi methodology will comprise a technical manual and operation logbook, and a competency assessment tool, which will be used for objectively approved entry and to monitor and measure adherence to agreed standards during the trial.

The video and photographic methodology will be validated for use during the COLOR III. Specialists who have interest in the TaTME technique (and preferably already have experience with the technique), can send an email to when interested in participating in the trial.

Main Investigators

Prof. H.J. Bonjer
Prof. H.J. Bonjer
Chair Department of Surgery, VU University Medical Centre, Amsterdam, The Netherlands
Prof. G.B. Hanna
Prof. G.B. Hanna
Head of Division of Surgery, Imperial College, London, UK
Prof. A.M. Lacy
Prof. A.M. Lacy
Chief Department of Gastrointestinal Surgery, Hospital Clinic, Barcelona, Spain
Prof. W.A. Bemelman
Prof. W.A. Bemelman
Professor of Surgery, Amsterdam Medical Centre, Amsterdam, The Netherlands
C. Sietses
C. Sietses
Colorectal surgeon, Gelderse Vallei Hospital, Ede, The Netherlands
R. Hompes
R. Hompes
Colorectal surgeon, Amsterdam Medical Center, Amsterdam, The Netherlands
J. Knol
J. Knol
Colorectal surgeon, Jessa Hospital, Hasselt, Belgium
J.B. Tuynman
J.B. Tuynman
Colorectal surgeon, VU University Medical Centre, Amsterdam, The Netherlands
A. Tsai
A. Tsai
PhD candidate, Imperial College London, London, UK
T.W.A Koedam
T.W.A Koedam
PhD candidate, VU University Medical Centre, Amsterdam, The Netherlands

Previous trial coordinator

S.E. van Oostendorp
S.E. van Oostendorp
PhD candidate, VU University Medical Centre, Amsterdam, The Netherlands

Current trial-coordinator

Participating Centers

The table below contains an overview of all the centers

that participate in the COLOR III Trial

bold = open for inclusion

The Netherlands

VU University Medical Center (VUmc), Amsterdam

Spaarne Gasthuis, Hoofddorp

Academic Medical Center (AMC), Amsterdam

Gelderse Vallei Hospital, Ede

IJsselland Hospital, Capelle a/d IJssel

OLVG, Amsterdam

Deventer ziekenhuis, Deventer

Zorgsaam Zeeuws-Vlaanderen, Terneuzen

Zuyderland Medical center, Sittard


Friendship Hosptial, Beijing

Ruijin Hospital, Shanghai


University Hospital Gent, Gent

Jessa Hospital, Hasselt


UMASS, Worchester

Florida Hospital Cancer Institute, Orlando


Health Sciences North, Sudbury


Royal Brisbane Hospital, Brisbane


Chinese Univeristy of Hongkong, Hongkong

Queen Mary Hospital, Hongkong University, Hongkong


Imperial College, London

Churchill Hospital, Oxford

St Mark’s Hospital, Harrow/ London


Slagelse Hospital, Slagelse


Caritas-KH St. Josef, Regensburg

Klinikum Leverkusen GmbH, Leverkusen

Rotkreuzklinikum, München

Charité – Universitätsmedizin, Berlin

St. Joseph Krankenhaus Berlin-Tempelhof, Berlin

Johanniter-Krankenhaus GmbH, Bonn

Asklepios Klinik, Langen

Universitätsklinikum, Leipzig

Ammerland Klinik, Ammerland

Universitats Klinikum Wurzburg, Wurzburg


Hospital de Braga, Braga


Krankenhaus der Barmherzigen Brüder, Graz


Uniwersytet Jagielloński Collegium Medicum, Krakow


University of Insubria, Varese

E. Agnelli Hospital, Pinerolo

Gradenigo Hospital, Turin

Gemelli Hospital, Rome

Ospedale S. Andrea, La Spezia


Sun Yat-Sen Cancer Center, Taipei

Veterans General Hospita, Taipei


Hospital Clinico, Valencia

Hospital Clínic, Barcelona

Fundación Jiménez Díaz, Madrid

Reina sofia university hospital, Murcia


Kantonsspital, St. Gallen


National Cancer Center, Goyang


National University Hospital, Singapore

Centers open for randomization